Products for Research Use Only

TSHB Polyclonal Antibody

CAT: 0749-ABP60782-01Size: 30 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0749-ABP60782-01Size:30 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. Thyroid stimulating hormone functions in the control of thyroid structure and metabolism. The protein encoded by TSHB is the beta subunit of thyroid stimulating hormone. Mutations in TSHB are associated with congenital central and secondary hypothyroidism and Hashimoto's thyroiditis. Alternative splicing of TSHB results in multiple transcript variants.
Description
Rabbit Anti-TSHB Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Thyroid-stimulating hormone subunit beta; Thyrotropin beta chain; INN: Thyrotropin alfa
Gene ID
7252
Accession Number
P01222
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from part region of human TSHB protein
Clonality
Polyclonal
Tag
TSHB
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
15kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of TSHB protein
Observed Molecular Weight
15
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Thyroid-stimulating hormone subunit beta; Thyrotropin beta chain; INN: Thyrotropin alfa
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P01222
Isotype
Rabbit IgG