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Tropomyosin α Polyclonal Antibody

CAT: 0749-ABP60765-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP60765-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TPM1 (Tropomyosin 1) is a Protein Coding gene. Diseases associated with TPM1 include Cardiomyopathy, Hypertrophic, 3 and Cardiomyopathy, Dilated, 1E. Among its related pathways are Striated Muscle Contraction and Dilated cardiomyopathy (DCM) . This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in TPM1 are associated with type 3 familial hypertrophic cardiomyopathy.
Description
Rabbit Anti-Tropomyosin α Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Tropomyosin alpha-1 chain; Alpha-tropomyosin; Tropomyosin-1
Gene ID
7168
Accession Number
P09493
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from part region of human Tropomyosin α protein at amino acid sequence of 101-150
Clonality
Polyclonal
Tag
Tropomyosin α
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
38kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of Tropomyosin α
Observed Molecular Weight
38
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:10000-20000
Other Product Names
Tropomyosin alpha-1 chain; Alpha-tropomyosin; Tropomyosin-1
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P09493
Isotype
Rabbit IgG

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