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TNPO1 Polyclonal Antibody

CAT: 0749-ABP60723-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP60723-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TNPO1 (Transportin 1) is a Protein Coding gene. Diseases associated with TNPO1 include Hiv-1 and Dementia, Frontotemporal. Among its related pathways are Development_TGF-beta receptor signaling and CDK-mediated phosphorylation and removal of Cdc6. TNPO1 encodes the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target nuclear proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins. Alternate splicing of TNPO1 results in two transcript variants encoding different proteins.
Description
Rabbit Anti-TNPO1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Transportin-1; Importin beta-2; Karyopherin beta-2; M9 region interaction protein; MIP
Gene ID
3842
Accession Number
Q92973
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human TNPO1 protein
Clonality
Polyclonal
Tag
TNPO1
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
98kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of TNPO1 protein
Observed Molecular Weight
98
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Transportin-1; Importin beta-2; Karyopherin beta-2; M9 region interaction protein; MIP
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q92973
Isotype
Rabbit IgG

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