THBG Polyclonal Antibody

CAT: 0749-ABP60671-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP60671-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
There are three proteins including thyroxine-binding globulin (TBG), transthyretin and albumin responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3) in the bloodstream. SERPINA7 (Serpin Family A Member 7) encodes the major thyroid hormone transport protein, TBG, in serum. It belongs to the serpin family in genomics, but the protein has no inhibitory function like many other members of the serpin family. Mutations in this gene result in TGB deficiency, which has been classified as partial deficiency, complete deficiency, and excess, based on the level of serum TBG. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.
Description
Rabbit Anti-THBG Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Thyroxine-binding globulin; Serpin A7; T4-binding globulin
Gene ID
6906
Accession Number
P05543
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from part region of human THBG protein
Clonality
Polyclonal
Tag
THBG
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
45kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of THBG protein
Observed Molecular Weight
45
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Thyroxine-binding globulin; Serpin A7; T4-binding globulin
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P05543
Isotype
Rabbit IgG

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