TERF2 Polyclonal Antibody

• Background :

  TERF2 encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic.

• Description :

  Rabbit Anti-TERF2 Polyclonal Antibody

• Product Name Alternative :

  Telomeric repeat-binding factor 2 ; TTAGGG repeat-binding factor 2; Telomeric DNA-binding protein

• Gene ID :

  7014

• Accession Number :

  Q15554

• Reactivity :

  Human, Mouse

• Immunogen :

  Synthesized peptide derived from part region of human TERF2 protein at amino acid sequence of 130-210

• Clonality :

  Polyclonal

• Tag :

  TERF2

• Applications :

  WB, ELISA

• Purification Method :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration :

  1 mg/ml

• Molecular Weight :

  55kD

• Precautions :

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions :

  Gel pack with blue ice.

• Storage Conditions :

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes :

  The antibody detects endogenous levels of TERF2 protein

• Observed Molecular Weight :

  55

• Formulation :

  Liquid solution

• Buffer pH :

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

• Applications Notes :

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

• Other Product Names :

  Telomeric repeat-binding factor 2 ; TTAGGG repeat-binding factor 2; Telomeric DNA-binding protein

• Tested Applications :

  WB, IHC, IF, IP, ELISA

• Host or Source :

  Rabbit

• Accession Number URL :

  http://www.uniprot.org/uniprot/Q15554

• CAS Number :

  9007-83-4

• Isotype :

  Rabbit IgG