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STAR3 Polyclonal Antibody

CAT: 0749-ABP60535-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP60535-01Size:30 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Sterol-binding protein that mediates cholesterol transport from the endoplasmic reticulum to endosomes (PubMed: 11053434, PubMed: 15930133, PubMed: 22514632, PubMed: 28377464) . Creates contact site between the endoplasmic reticulum and late endosomes: localizes to late endosome membranes and contacts the endoplasmic reticulum via interaction with VAPA and VAPB (PubMed: 24105263, PubMed: 28377464) . Acts as a lipid transfer protein that redirects sterol to the endosome at the expense of the cell membrane and favors membrane formation inside endosomes (PubMed: 28377464) . May also mediate cholesterol transport between other membranes, such as mitochondria membrane or cell membrane (PubMed: 12070139, PubMed: 19965586) . However, such results need additional experimental evidences; probably mainly mediates cholesterol transport from the endoplasmic reticulum to endosomes (PubMed: 28377464) . Does not activate transcriptional cholesterol sensing (PubMed: 28377464) . Able to bind other lipids, such as lutein, a xanthophyll carotenoids that form the macular pigment of the retina (PubMed: 21322544) .
Description
Rabbit Anti-STAR3 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
StAR-related lipid transfer protein 3; Metastatic lymph node gene 64 protein; MLN 64; Protein CAB1; START domain-containing protein 3; StARD3
Gene ID
10948
Accession Number
Q14849
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human STAR3 protein
Clonality
Polyclonal
Tag
STAR3
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
48kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of STAR3 protein
Observed Molecular Weight
48
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
StAR-related lipid transfer protein 3; Metastatic lymph node gene 64 protein; MLN 64; Protein CAB1; START domain-containing protein 3; StARD3
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q14849
Isotype
Rabbit IgG

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