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SPTN4 Polyclonal Antibody

CAT: 0749-ABP60503-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP60503-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is composed of two antiparallel dimers of alpha- and beta- subunits. SPTBN4 is one member of a family of beta-spectrin genes. The encoded protein localizes to the nuclear matrix, PML nuclear bodies, and cytoplasmic vesicles. A highly similar gene in the mouse is required for localization of specific membrane proteins in polarized regions of neurons. Multiple transcript variants encoding different isoforms have been found for SPTBN4.
Description
Rabbit Anti-SPTN4 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Spectrin beta chain, non-erythrocytic 4; Beta-IV spectrin; Spectrin, non-erythroid beta chain 3
Gene ID
57731
Accession Number
Q9H254
Reactivity
Human
Immunogen
Synthesized peptide derived from part region of human SPTN4 protein
Clonality
Polyclonal
Tag
SPTN4
Applications
IHC, IF
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
282kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of SPTN4 protein
Observed Molecular Weight
282
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-300; IF 1:50-200
Other Product Names
Spectrin beta chain, non-erythrocytic 4; Beta-IV spectrin; Spectrin, non-erythroid beta chain 3
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q9H254
Isotype
Rabbit IgG

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