SLAF6 Polyclonal Antibody

• Background :

  The protein encoded by SLAMF6 is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs) . It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

• Description :

  Rabbit Anti-SLAF6 Polyclonal Antibody

• Product Name Alternative :

  SLAM family member 6; Activating NK receptor; NK-T-B-antigen; NTB-A; CD_antigen: CD352

• Gene ID :

  114836

• Accession Number :

  Q96DU3

• Reactivity :

  Human, Mouse

• Immunogen :

  Synthesized peptide derived from part region of human SLAF6 protein at amino acid sequence of 20-100

• Clonality :

  Polyclonal

• Tag :

  SLAF6

• Applications :

  WB, ELISA

• Purification Method :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration :

  1 mg/ml

• Molecular Weight :

  36kD

• Precautions :

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions :

  Gel pack with blue ice.

• Storage Conditions :

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes :

  The antibody detects endogenous levels of SLAF6 protein

• Observed Molecular Weight :

  36

• Formulation :

  Liquid solution

• Buffer pH :

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

• Applications Notes :

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

• Other Product Names :

  SLAM family member 6; Activating NK receptor; NK-T-B-antigen; NTB-A; CD_antigen: CD352

• Tested Applications :

  WB, IHC, IF, IP, ELISA

• Host or Source :

  Rabbit

• Accession Number URL :

  http://www.uniprot.org/uniprot/Q96DU3

• CAS Number :

  9007-83-4

• Isotype :

  Rabbit IgG