RNF6 Polyclonal Antibody

CAT: 0749-ABP60222-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP60222-01Size:30 µL
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Background
RNF6 (Ring Finger Protein 6) is a Protein Coding gene. Diseases associated with RNF6 include Esophageal Cancer and Squamous Cell Carcinoma. Among its related pathways are Class I MHC mediated antigen processing and presentation and Androgen receptor signaling pathway. The protein encoded by RNF6 contains a RING-H2 finger motif. Deletions and mutations in RNF6 were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed.
Description
Rabbit Anti-RNF6 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
E3 ubiquitin-protein ligase RNF6; RING-type E3 ubiquitin transferase RNF6
Gene ID
6049
Accession Number
Q9Y252
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human RNF6 protein at amino acid sequence of 470-550
Clonality
Polyclonal
Tag
RNF6
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
75kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of RNF6 protein
Observed Molecular Weight
75
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
E3 ubiquitin-protein ligase RNF6; RING-type E3 ubiquitin transferase RNF6
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q9Y252
Isotype
Rabbit IgG

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