RNF6 Polyclonal Antibody

• Background:

  RNF6 (Ring Finger Protein 6) is a Protein Coding gene. Diseases associated with RNF6 include Esophageal Cancer and Squamous Cell Carcinoma. Among its related pathways are Class I MHC mediated antigen processing and presentation and Androgen receptor signaling pathway. The protein encoded by RNF6 contains a RING-H2 finger motif. Deletions and mutations in RNF6 were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed.

• Description:

  Rabbit Anti-RNF6 Polyclonal Antibody

• Product Name Alternative:

  E3 ubiquitin-protein ligase RNF6; RING-type E3 ubiquitin transferase RNF6

• Gene ID:

  6049

• Accession Number:

  Q9Y252

• Reactivity:

  Human, Mouse

• Immunogen:

  Synthesized peptide derived from part region of human RNF6 protein at amino acid sequence of 470-550

• Clonality:

  Polyclonal

• Tag:

  RNF6

• Applications:

  WB, ELISA

• Purification Method:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration:

  1 mg/ml

• Molecular Weight:

  75kD

• Precautions:

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions:

  Gel pack with blue ice.

• Storage Conditions:

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes:

  The antibody detects endogenous levels of RNF6 protein

• Observed Molecular Weight:

  75

• Formulation:

  Liquid solution

• Buffer pH:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

• Applications Notes:

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

• Other Product Names:

  E3 ubiquitin-protein ligase RNF6; RING-type E3 ubiquitin transferase RNF6

• Tested Applications:

  WB, IHC, IF, IP, ELISA

• Host or Source:

  Rabbit

• Accession Number URL:

  http://www.uniprot.org/uniprot/Q9Y252

• CAS Number:

  9007-83-4

• Isotype:

  Rabbit IgG