RIPK1 Polyclonal Antibody

CAT: 0749-ABP60179-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP60179-01Size:30 µL
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Background
RIPK1 encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. Receptor Interacting Serine/Threonine Kinase 1 plays a role in inflammation and cell death in response to tissue damage, pathogen recognition, and as part of developmental regulation. RIPK1/RIPK3 kinase-mediated necrosis is referred to as necroptosis. Genetic disruption of this gene in mice results in death shortly after birth.
Description
Rabbit Anti-RIPK1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Receptor-interacting serine/threonine-protein kinase 1; Cell death protein RIP; Receptor-interacting protein 1; RIP-1; Serine/threonine-protein kinase RIP
Gene ID
8737
Accession Number
Q13546
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human RIPK1 protein
Clonality
Polyclonal
Tag
RIPK1
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
73kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of RIPK1 protein
Observed Molecular Weight
73
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Receptor-interacting serine/threonine-protein kinase 1; Cell death protein RIP; Receptor-interacting protein 1; RIP-1; Serine/threonine-protein kinase RIP
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q13546
Isotype
Rabbit IgG

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