RBBP6 Polyclonal Antibody

CAT: 0749-ABP60112-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP60112-01Size:30 µL
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Background
The retinoblastoma tumor suppressor (pRB) protein binds with many other proteins. In various human cancers, pRB suppresses cellular proliferation and is inactivated. Cell cycle-dependent phosphorylation regulates the activity of pRB. RBBP6 (RB Binding Protein 6, Ubiquitin Ligase) encodes a protein which binds to underphosphorylated but not phosphorylated pRB. Multiple alternatively spliced transcript variants that encode different isoforms have been found for RBBP6.
Description
Rabbit Anti-RBBP6 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
E3 ubiquitin-protein ligase RBBP6; Proliferation potential-related protein; Protein P2P-R; RING-type E3 ubiquitin transferase RBBP6; Retinoblastoma-binding Q protein 1; RBQ-1; Retinoblastoma-binding protein 6; p53-associated cellular protein of testis
Gene ID
5930
Accession Number
Q7Z6E9
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human RBBP6 protein at amino acid sequence of 270-350
Clonality
Polyclonal
Tag
RBBP6
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
197kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of RBBP6 protein
Observed Molecular Weight
197
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
E3 ubiquitin-protein ligase RBBP6; Proliferation potential-related protein; Protein P2P-R; RING-type E3 ubiquitin transferase RBBP6; Retinoblastoma-binding Q protein 1; RBQ-1; Retinoblastoma-binding protein 6; p53-associated cellular protein of testis
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q7Z6E9
Isotype
Rabbit IgG

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