Products for Research Use Only

RAP1A Polyclonal Antibody

CAT: 0749-ABP60089-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP60089-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
RAP1A encodes a member of the Ras family of small GTPases. The encoded protein undergoes a change in conformational state and activity, depending on whether it is bound to GTP or GDP. This protein is activated by several types of guanine nucleotide exchange factors (GEFs), and inactivated by two groups of GTPase-activating proteins (GAPs) . The activation status of the encoded protein is therefore affected by the balance of intracellular levels of GEFs and GAPs. The encoded protein regulates signaling pathways that affect cell proliferation and adhesion, and may play a role in tumor malignancy. Pseudogenes of RAP1A have been defined on chromosomes 14 and 17. Alternative splicing results in multiple transcript variants.
Description
Rabbit Anti-RAP1A Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
C21KG; G-22K; GTP-binding protein smg p21A; Ras-related protein Krev-1
Gene ID
5906
Accession Number
P62834
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from part region of human RAP1A protein
Clonality
Polyclonal
Tag
RAP1A
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
20kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of RAP1A protein
Observed Molecular Weight
20
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
C21KG; G-22K; GTP-binding protein smg p21A; Ras-related protein Krev-1
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P62834
Isotype
Rabbit IgG