RAB21 Polyclonal Antibody

• Background:

  RAB21 (RAB21, Member RAS Oncogene Family) belongs to the Rab family of monomeric GTPases, which are involved in the control of cellular membrane traffic. The encoded protein plays a role in the targeted trafficking of integrins via its association with integrin alpha tails. As a consequence, the encoded protein is involved in the regulation of cell adhesion and migration. Expression of RAB21 is associated with a poor prognosis for glioma patients. RAB21 is downregulated by the tumor suppressor miR-200b and miRNA-200b is itself downregulated in glioma tissues.

• Description:

  Rabbit Anti-RAB21 Polyclonal Antibody

• Product Name Alternative:

  Ras-related protein Rab-21

• Gene ID:

  23011

• Accession Number:

  Q9UL25

• Reactivity:

  Human, Rat, Mouse

• Immunogen:

  Synthesized peptide derived from part region of human RAB21 protein at amino acid sequence of 60-140

• Clonality:

  Polyclonal

• Tag:

  RAB21

• Applications:

  WB, ELISA

• Purification Method:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration:

  1 mg/ml

• Molecular Weight:

  24kD

• Precautions:

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions:

  Gel pack with blue ice.

• Storage Conditions:

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes:

  The antibody detects endogenous levels of RAB21 protein

• Observed Molecular Weight:

  24

• Formulation:

  Liquid solution

• Buffer pH:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

• Applications Notes:

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

• Other Product Names:

  Ras-related protein Rab-21

• Tested Applications:

  WB, IHC, IF, IP, ELISA

• Host or Source:

  Rabbit

• Accession Number URL:

  http://www.uniprot.org/uniprot/Q9UL25

• CAS Number:

  9007-83-4

• Isotype:

  Rabbit IgG