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PZP Polyclonal Antibody

CAT: 0749-ABP60051-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP60051-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the ‘bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced) . Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.
Description
Rabbit Anti-PZP Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Pregnancy zone protein; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 6
Gene ID
5858
Accession Number
P20742
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human PZP protein at amino acid sequence of 1301-1350
Clonality
Polyclonal
Tag
PZP
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
163kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of PZP protein
Observed Molecular Weight
163
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Pregnancy zone protein; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 6
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P20742
Isotype
Rabbit IgG

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