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PTN18 Polyclonal Antibody

CAT: 0749-ABP60030-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP60030-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PTPN18 (Protein Tyrosine Phosphatase, Non-Receptor Type 18) is a Protein Coding gene. Among its related pathways are Signaling by ERBB2 and PAK Pathway. The protein encoded by PTPN18 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, the mitotic cycle, and oncogenic transformation. PTPN18 contains a PEST motif, which often serves as a protein-protein interaction domain, and may be related to protein intracellular half-live. This protein can differentially dephosphorylate autophosphorylated tyrosine kinases that are overexpressed in tumor tissues, and it appears to regulate HER2, a member of the epidermal growth factor receptor family of receptor tyrosine kinases. Two transcript variants encoding different isoforms have been found for PTPN18.
Description
Rabbit Anti-PTN18 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Tyrosine-protein phosphatase non-receptor type 18; Brain-derived phosphatase
Gene ID
26469
Accession Number
Q99952
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human PTN18 protein
Clonality
Polyclonal
Tag
PTN18
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
50kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of PTN18 protein
Observed Molecular Weight
50
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Tyrosine-protein phosphatase non-receptor type 18; Brain-derived phosphatase
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q99952
Isotype
Rabbit IgG

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