PRP8 Polyclonal Antibody

CAT: 0749-ABP60011-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP60011-01Size:30 µL
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Background
Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by PRPF8 (Pre-MRNA Processing Factor 8) is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. PRPF8 is a candidate gene for autosomal dominant retinitis pigmentosa.
Description
Rabbit Anti-PRP8 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Pre-mRNA-processing-splicing factor 8; 220 kDa U5 snRNP-specific protein; PRP8 homolog; Splicing factor Prp8; p220
Gene ID
10594
Accession Number
Q6P2Q9
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human PRP8 protein at amino acid sequence of 160-240
Clonality
Polyclonal
Tag
PRP8
Applications
IHC, IF
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
256kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of PRP8 protein
Observed Molecular Weight
256
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-300; IF 1:50-200
Other Product Names
Pre-mRNA-processing-splicing factor 8; 220 kDa U5 snRNP-specific protein; PRP8 homolog; Splicing factor Prp8; p220
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q6P2Q9
Isotype
Rabbit IgG

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