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PLS3 Polyclonal Antibody

CAT: 0749-ABP59947-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP59947-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Seems to play a role in apoptosis, through translocation of cardiolipin from the inner to the outer mitochondrial membrane which promotes BID recruitment and enhances tBid-induced mitochondrial damages.
Description
Rabbit Anti-PLS3 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Phospholipid scramblase 3; PL scramblase 3; Ca (2+) -dependent phospholipid scramblase 3
Gene ID
57048
Accession Number
Q9NRY6
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from part region of human PLS3 protein at amino acid sequence of 180-260
Clonality
Polyclonal
Tag
PLS3
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
32kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of PLS3 protein
Observed Molecular Weight
32
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Phospholipid scramblase 3; PL scramblase 3; Ca (2+) -dependent phospholipid scramblase 3
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q9NRY6
Isotype
Rabbit IgG

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