PLEC Polyclonal Antibody

• Background :

  PLEC (Plectin) is a Protein Coding gene. Diseases associated with PLEC include Epidermolysis Bullosa Simplex, Ogna Type and Muscular Dystrophy, Limb-Girdle, Type 2Q. Among its related pathways are Cytoskeleton remodeling Neurofilaments and Collagen chain trimerization. PLEC is a prominent member of an important family of structurally and in part functionally related proteins, termed plakins or cytolinkers, that are capable of interlinking different elements of the cytoskeleton.

• Description :

  Rabbit Anti-PLEC Polyclonal Antibody

• Product Name Alternative :

  Plectin; PCN; PLTN; Hemidesmosomal protein 1; HD1; Plectin-1

• Gene ID :

  5339

• Accession Number :

  Q15149

• Reactivity :

  Human, Rat, Mouse

• Immunogen :

  Synthesized peptide derived from part region of human PLEC protein at amino acid sequence of 240-320

• Clonality :

  Polyclonal

• Tag :

  PLEC

• Applications :

  IHC, IF

• Purification Method :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration :

  1 mg/ml

• Molecular Weight :

  515kD

• Precautions :

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions :

  Gel pack with blue ice.

• Storage Conditions :

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes :

  The antibody detects endogenous levels of PLEC protein

• Observed Molecular Weight :

  515

• Formulation :

  Liquid solution

• Buffer pH :

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

• Applications Notes :

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-300; IF 1:50-200

• Other Product Names :

  Plectin; PCN; PLTN; Hemidesmosomal protein 1; HD1; Plectin-1

• Tested Applications :

  WB, IHC, IF, IP, ELISA

• Host or Source :

  Rabbit

• Accession Number URL :

  http://www.uniprot.org/uniprot/Q15149

• CAS Number :

  9007-83-4

• Isotype :

  Rabbit IgG