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PLEC Polyclonal Antibody

CAT: 0749-ABP59939-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP59939-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PLEC (Plectin) is a Protein Coding gene. Diseases associated with PLEC include Epidermolysis Bullosa Simplex, Ogna Type and Muscular Dystrophy, Limb-Girdle, Type 2Q. Among its related pathways are Cytoskeleton remodeling Neurofilaments and Collagen chain trimerization. PLEC is a prominent member of an important family of structurally and in part functionally related proteins, termed plakins or cytolinkers, that are capable of interlinking different elements of the cytoskeleton.
Description
Rabbit Anti-PLEC Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Plectin; PCN; PLTN; Hemidesmosomal protein 1; HD1; Plectin-1
Gene ID
5339
Accession Number
Q15149
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from part region of human PLEC protein at amino acid sequence of 240-320
Clonality
Polyclonal
Tag
PLEC
Applications
IHC, IF
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
515kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of PLEC protein
Observed Molecular Weight
515
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-300; IF 1:50-200
Other Product Names
Plectin; PCN; PLTN; Hemidesmosomal protein 1; HD1; Plectin-1
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q15149
Isotype
Rabbit IgG

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