PIGC Polyclonal Antibody

CAT: 0749-ABP59911-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP59911-01Size:30 µL
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Background
PIGC (Phosphatidylinositol Glycan Anchor Biosynthesis Class C) is a Protein Coding gene. Diseases associated with PIGC include Autosomal Recessive Non-Syndromic Intellectual Disability and Lassa Fever. Among its related pathways are Glycosylphosphatidylinositol (GPI) -anchor biosynthesis and Metabolism. PIGC encodes an endoplasmic reticulum associated protein that is involved in glycosylphosphatidylinositol (GPI) lipid anchor biosynthesis. The GPI lipid anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. The encoded protein is one subunit of the GPI N-acetylglucosaminyl (GlcNAc) transferase that transfers GlcNAc to phosphatidylinositol (PI) on the cytoplasmic side of the endoplasmic reticulum. Two alternatively spliced transcripts that encode the same protein have been found for PIGC. A pseudogene on chromosome 11 has also been characterized.
Description
Rabbit Anti-PIGC Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Phosphatidylinositol N-acetylglucosaminyltransferase subunit C; Phosphatidylinositol-glycan biosynthesis class C protein; PIG-C
Gene ID
5279
Accession Number
Q92535
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from part region of human PIGC protein at amino acid sequence of 170-250
Clonality
Polyclonal
Tag
PIGC
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
32kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of PIGC protein
Observed Molecular Weight
32
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Phosphatidylinositol N-acetylglucosaminyltransferase subunit C; Phosphatidylinositol-glycan biosynthesis class C protein; PIG-C
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q92535
Isotype
Rabbit IgG

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