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PHX2A Polyclonal Antibody

CAT: 0749-ABP59900-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP59900-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PHOX2A (Paired Like Homeobox 2a) is a Protein Coding gene. Diseases associated with PHOX2A include Fibrosis Of Extraocular Muscles, Congenital, 2 and Tukel Syndrome. Among its related pathways are Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways. The protein encoded by PHOX2A contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene.
Description
Rabbit Anti-PHX2A Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Paired mesoderm homeobox protein 2A; ARIX1 homeodomain protein; Aristaless homeobox protein homolog; Paired-like homeobox 2A
Gene ID
401
Accession Number
O14813
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from part region of human PHX2A protein at amino acid sequence of 210-290
Clonality
Polyclonal
Tag
PHX2A
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
31kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of PHX2A protein
Observed Molecular Weight
31
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Paired mesoderm homeobox protein 2A; ARIX1 homeodomain protein; Aristaless homeobox protein homolog; Paired-like homeobox 2A
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/O14813
Isotype
Rabbit IgG

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