PHB2 Polyclonal Antibody

CAT: 0749-ABP59895-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP59895-01Size:30 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PHB2 (Prohibitin 2) is a Protein Coding gene. Diseases associated with PHB2 include Urethritis and Loiasis. Among its related pathways are GPCR Pathway and MAPK Signaling: mitogen Stimulation Pathway. GO annotations related to this gene include estrogen receptor binding. Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity) . Functions as an estrogen receptor (ER) -selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.
Description
Rabbit Anti-PHB2 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
B-cell receptor-associated protein BAP37; D-prohibitin; Repressor of estrogen receptor activity
Gene ID
11331
Accession Number
Q99623
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from part region of human PHB2 protein
Clonality
Polyclonal
Tag
PHB2
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
32kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of PHB2 protein
Observed Molecular Weight
32
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
B-cell receptor-associated protein BAP37; D-prohibitin; Repressor of estrogen receptor activity
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q99623
Isotype
Rabbit IgG

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