PF-4 Polyclonal Antibody

• Background :

  PF-4 encodes a member of the CXC chemokine family. This chemokine is released from the alpha granules of activated platelets in the form of a homotetramer which has high affinity for heparin and is involved in platelet aggregation. PF-4is chemotactic for numerous other cell type and also functions as an inhibitor of hematopoiesis, angiogenesis and T-cell function. The protein also exhibits antimicrobial activity against Plasmodium falciparum. PF4 (Platelet Factor 4) is a Protein Coding gene. Diseases associated with PF4 include Erythromelalgia and Thrombocytopenia. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Akt Signaling.

• Description :

  Rabbit Anti-PF-4 Polyclonal Antibody

• Product Name Alternative :

  Platelet factor 4; PF-4; C-X-C motif chemokine 4; Iroplact; Oncostatin-A

• Gene ID :

  5196

• Accession Number :

  P02776

• Reactivity :

  Human, Rat

• Immunogen :

  Synthesized peptide derived from part region of human PF-4 protein at amino acid sequence of 51-100

• Clonality :

  Polyclonal

• Tag :

  PF-4

• Applications :

  WB, ELISA, IHC

• Purification Method :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration :

  1 mg/ml

• Precautions :

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions :

  Gel pack with blue ice.

• Storage Conditions :

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes :

  The antibody detects endogenous levels of PF-4

• Formulation :

  Liquid solution

• Buffer pH :

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applications Notes :

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000

• Other Product Names :

  Platelet factor 4; PF-4; C-X-C motif chemokine 4; Iroplact; Oncostatin-A

• Tested Applications :

  WB, IHC, IF, IP, ELISA

• Host or Source :

  Rabbit

• Accession Number URL :

  http://www.uniprot.org/uniprot/P02776

• CAS Number :

  9007-83-4

• Isotype :

  Rabbit IgG