PARP9 Polyclonal Antibody

• Background :

  PARP9 (Poly (ADP-Ribose) Polymerase Family Member 9) is a Protein Coding gene. Diseases associated with PARP9 include B-Cell Lymphomas and Lymphoma. Among its related pathways are Metabolism and Metabolism of water-soluble vitamins and cofactors. GO annotations related to this gene include NAD+ ADP-ribosyltransferase activity. An important paralog of this gene is PARP14. In concert with DTX3L plays a role in PARP1-dependent DNA damage repair. PARP1-dependent PARP9/BAL1-DTX3L-mediated ubiquitination promotes the rapid and specific recruitment of 53BP1/TP53BP1, UIMC1/RAP80, and BRCA1 to DNA damage sites. Involved in inducing the expression of IFN-gamma-responsive genes.

• Description :

  Rabbit Anti-PARP9 Polyclonal Antibody

• Product Name Alternative :

  Poly [ADP-ribose] polymerase 9; PARP-9; ADP-ribosyltransferase diphtheria toxin-like 9; ARTD9; B aggressive lymphoma protein

• Gene ID :

  83666

• Accession Number :

  Q8IXQ6

• Reactivity :

  Human, Mouse

• Immunogen :

  Synthesized peptide derived from part region of human PARP9 protein at amino acid sequence of 450-530

• Clonality :

  Polyclonal

• Tag :

  PARP9

• Applications :

  WB, ELISA

• Purification Method :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration :

  1 mg/ml

• Molecular Weight :

  93kD

• Precautions :

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions :

  Gel pack with blue ice.

• Storage Conditions :

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes :

  The antibody detects endogenous levels of PARP9 protein

• Observed Molecular Weight :

  93

• Formulation :

  Liquid solution

• Buffer pH :

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

• Applications Notes :

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

• Other Product Names :

  Poly [ADP-ribose] polymerase 9; PARP-9; ADP-ribosyltransferase diphtheria toxin-like 9; ARTD9; B aggressive lymphoma protein

• Tested Applications :

  WB, IHC, IF, IP, ELISA

• Host or Source :

  Rabbit

• Accession Number URL :

  http://www.uniprot.org/uniprot/Q8IXQ6

• CAS Number :

  9007-83-4

• Isotype :

  Rabbit IgG