Products for Research Use Only
RegisterLogin

PABP4 Polyclonal Antibody

CAT: 0749-ABP59808-01Size: 30 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0749-ABP59808-01Size:30 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Poly (A) -binding proteins (PABPs) bind to the poly (A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules. Alternatively spliced transcript variants encoding different isoforms have been found for PABPC4.
Description
Rabbit Anti-PABP4 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Polyadenylate-binding protein 4; PABP-4; Poly (A) -binding protein 4; Activated-platelet protein 1; APP-1; Inducible poly (A) -binding protein; iPABP
Gene ID
8761
Accession Number
Q13310
Reactivity
Human
Immunogen
Synthesized peptide derived from part region of human PABP4 protein at amino acid sequence of 190-270
Clonality
Polyclonal
Tag
PABP4
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
70kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of PABP4 protein
Observed Molecular Weight
70
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Polyadenylate-binding protein 4; PABP-4; Poly (A) -binding protein 4; Activated-platelet protein 1; APP-1; Inducible poly (A) -binding protein; iPABP
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q13310
Isotype
Rabbit IgG

Related Products

CatalogName
ABP59807-01PABP2 Polyclonal Antibody
ABP53830-01PABP5 Polyclonal Antibody
ANT-13638-50ugPABPC4 Polyclonal Antibody
ABP59806-01PABP1 Polyclonal Antibody
ABP55455-01PABP3 Polyclonal Antibody
ANT-13638-100ugPABPC4 Polyclonal Antibody
ANT-13843-100ugPolyclonal Antibody
ANT-15047-100ugWAS Polyclonal Antibody
ANT-15047-50ugWAS Polyclonal Antibody
ANT-13843-50ugPolyclonal Antibody

Alternative Products

CatalogName
BT-AP12724-01PABP4 Polyclonal Antibody
E28PN1071PABP4 Rabbit Polyclonal Antibody
WP1495-01U-Blot® PABP4 Polyclonal Antibody
STJ191175Anti-PABP4 antibody
GTR18219303-01Rabbit PABP4 Antibody
GTR18213827-01Rabbit PABP4 IHC Antibody
MBS3901957-01Rabbit anti-PABP4 Antibody, Affinity Purified
IHC-00561Rabbit anti-PABP4 IHC Antibody, Affinity Purified
APR12525GPolyclonal MeCP2 polyclonal antibody
APR00376GPolyclonal BMI1 polyclonal antibody

Popular Products