OSTCN Polyclonal Antibody

CAT: 0749-ABP59775-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP59775-01Size:30 µL
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Background
BGLAP encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. Bone Gamma-Carboxyglutamate Protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product.
Description
Rabbit Anti-OSTCN Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Osteocalcin; Bone Gla protein; BGP; Gamma-carboxyglutamic acid-containing protein
Gene ID
632
Accession Number
P02818
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from part region of human OSTCN protein
Clonality
Polyclonal
Tag
OSTCN
Applications
WB IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
11kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of OSTCN protein
Observed Molecular Weight
11
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IF 1:100-300; ELISA 1:5000-20000; Not yet tested in other applications.
Other Product Names
Osteocalcin; Bone Gla protein; BGP; Gamma-carboxyglutamic acid-containing protein
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P02818
Isotype
Rabbit IgG

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