NOX4 Polyclonal Antibody

CAT: 0749-ABP59498-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP59498-01Size:30 µL
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Background
NOX4 gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS) . The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.
Description
Rabbit Anti-NOX4 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
NADPH oxidase 4; KOX-1; Kidney superoxide-producing NADPH oxidase; Renal NAD (P) H-oxidase
Gene ID
50507
Accession Number
Q9NPH5
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from part region of human NOX4 protein
Clonality
Polyclonal
Tag
NOX4
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
63kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of NOX4 protein
Observed Molecular Weight
63
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
NADPH oxidase 4; KOX-1; Kidney superoxide-producing NADPH oxidase; Renal NAD (P) H-oxidase
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q9NPH5
Isotype
Rabbit IgG

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