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NFX1 Polyclonal Antibody

CAT: 0749-ABP59457-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP59457-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. The protein encoded by NFX1 (Nuclear Transcription Factor, X-Box Binding 1) is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma. Three alternative splice variants, each of which encodes a different isoform, have been identified.
Description
Rabbit Anti-NFX1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Transcriptional repressor NF-X1; Nuclear transcription factor, X box-binding protein 1
Gene ID
4799
Accession Number
Q12986
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human NFX1 protein at amino acid sequence of 80-160
Clonality
Polyclonal
Tag
NFX1
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
123kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of NFX1 protein
Observed Molecular Weight
123
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Transcriptional repressor NF-X1; Nuclear transcription factor, X box-binding protein 1
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q12986
Isotype
Rabbit IgG

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