NEUS Polyclonal Antibody

CAT: 0749-ABP59450-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP59450-01Size:30 µL
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Background
SERPINI1 gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a dominantly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Description
Rabbit Anti-NEUS Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Neuroserpin; Peptidase inhibitor 12; PI-12; Serpin I1
Gene ID
5274
Accession Number
Q99574
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from part region of human NEUS protein
Clonality
Polyclonal
Tag
NEUS
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
45kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of NEUS protein
Observed Molecular Weight
45
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Neuroserpin; Peptidase inhibitor 12; PI-12; Serpin I1
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q99574
Isotype
Rabbit IgG

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