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NEK3 Polyclonal Antibody

CAT: 0749-ABP59443-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP59443-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
NEK3 encodes a member of the NimA (never in mitosis A) family of serine/threonine protein kinases. NIMA Related Kinase 3 differs from other NimA family members in that it is not cell cycle regulated and is found primarily in the cytoplasm. The kinase is activated by prolactin stimulation, leading to phosphorylation of VAV2 guanine nucleotide exchange factor, paxillin, and activation of the RAC1 GTPase. Multiple transcript variants encoding different isoforms have been found for this gene.
Description
Rabbit Anti-NEK3 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Serine/threonine-protein kinase Nek3; HSPK 36; Never in mitosis A-related kinase 3; NimA-related protein kinase 3
Gene ID
4752
Accession Number
P51956
Reactivity
Mouse
Immunogen
Synthesized peptide derived from part region of human NEK3 protein
Clonality
Polyclonal
Tag
NEK3
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
55kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of NEK3 protein
Observed Molecular Weight
55
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Serine/threonine-protein kinase Nek3; HSPK 36; Never in mitosis A-related kinase 3; NimA-related protein kinase 3
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P51956
Isotype
Rabbit IgG

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