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N2DL2 Polyclonal Antibody

CAT: 0749-ABP59387-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP59387-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ULBP2 encodes a major histocompatibility complex (MHC) class I-related molecule that binds to the NKG2D receptor on natural killer (NK) cells to trigger release of multiple cytokines and chemokines that in turn contribute to the recruitment and activation of NK cells. The encoded protein undergoes further processing to generate the mature protein that is either anchored to membrane via a glycosylphosphatidylinositol moiety, or secreted. Many malignant cells secrete the encoded protein to evade immunosurveillance by NK cells. ULBP2 is located in a cluster of multiple MHC class I-related genes on chromosome 6. ULBP2 (UL16 Binding Protein 2) is a Protein Coding gene. Among its related pathways are Immune response Role of DAP12 receptors in NK cells and p53 Pathway (RnD) .
Description
Rabbit Anti-N2DL2 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
UL16-binding protein 2; ALCAN-alpha; NKG2D ligand 2; N2DL-2; NKG2DL2; Retinoic acid early transcript 1H
Gene ID
80328
Accession Number
Q9BZM5
Reactivity
Human
Immunogen
Synthesized peptide derived from part region of human N2DL2 protein
Clonality
Polyclonal
Tag
N2DL2
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
27kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of N2DL2 protein
Observed Molecular Weight
27
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
UL16-binding protein 2; ALCAN-alpha; NKG2D ligand 2; N2DL-2; NKG2DL2; Retinoic acid early transcript 1H
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q9BZM5
Isotype
Rabbit IgG

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