MYO7A Polyclonal Antibody

• Background :

  MYO7A (Myosin VIIA) is a Protein Coding gene. Among its related pathways are Sertoli-Sertoli Cell Junction Dynamics and Actin Nucleation by ARP-WASP Complex. MYO7A is a member of the myosin gene family. Myosins are mechanochemical proteins characterized by the presence of a motor domain, an actin-binding domain, a neck domain that interacts with other proteins, and a tail domain that serves as an anchor. MYO7A encodes an unconventional myosin with a very short tail. Defects in MYO7A are associated with the mouse shaker-1 phenotype and the human Usher syndrome 1B which are characterized by deafness, reduced vestibular function, and (in human) retinal degeneration. Alternative splicing results in multiple transcript variants.

• Description :

  Rabbit Anti-MYO7A Polyclonal Antibody

• Product Name Alternative :

  Unconventional myosin-VIIa

• Gene ID :

  4647

• Accession Number :

  Q13402

• Reactivity :

  Human, Mouse

• Immunogen :

  Synthesized peptide derived from part region of human MYO7A protein at amino acid sequence of 830-910

• Clonality :

  Polyclonal

• Tag :

  MYO7A

• Applications :

  WB, ELISA

• Purification Method :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration :

  1 mg/ml

• Molecular Weight :

  243kD

• Precautions :

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions :

  Gel pack with blue ice.

• Storage Conditions :

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes :

  The antibody detects endogenous levels of MYO7A protein

• Observed Molecular Weight :

  243

• Formulation :

  Liquid solution

• Buffer pH :

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

• Applications Notes :

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

• Other Product Names :

  Unconventional myosin-VIIa

• Tested Applications :

  WB, IHC, IF, IP, ELISA

• Host or Source :

  Rabbit

• Accession Number URL :

  http://www.uniprot.org/uniprot/Q13402

• CAS Number :

  9007-83-4

• Isotype :

  Rabbit IgG