Products for Research Use Only

MUC5B Polyclonal Antibody

CAT: 0749-ABP59344-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP59344-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MUC5B (Mucin 5B, Oligomeric Mucus/Gel-Forming) is a Protein Coding gene. Diseases associated with MUC5B include Pulmonary Fibrosis, Idiopathic and Pneumonia. Among its related pathways are O-linked glycosylation and HIV Life Cycle. MUC5B encodes a member of the mucin family of proteins, which are highly glycosylated macromolecular components of mucus secretions. This family member is the major gel-forming mucin in mucus. It is a major contributor to the lubricating and viscoelastic properties of whole saliva, normal lung mucus and cervical mucus. MUC5B has been found to be up-regulated in some human diseases, including sinus mucosa of chronic rhinosinusitis (CRS), CRS with nasal polyposis, chronic obstructive pulmonary disease (COPD) and H. pylori-associated gastric disease, and it may be involved in the pathogenesis of these diseases.
Description
Rabbit Anti-MUC5B Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Mucin-5B; MUC-5B; Cervical mucin; High molecular weight salivary mucin MG1; Mucin-5 subtype B, tracheobronchial; Sublingual gland mucin
Gene ID
727897
Accession Number
Q9HC84
Reactivity
Human
Immunogen
Synthesized peptide derived from part region of human MUC5B protein at amino acid sequence of 1810-1890
Clonality
Polyclonal
Tag
MUC5B
Applications
IHC, IF
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
633kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of MUC5B protein
Observed Molecular Weight
633
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-300; IF 1:50-200
Other Product Names
Mucin-5B; MUC-5B; Cervical mucin; High molecular weight salivary mucin MG1; Mucin-5 subtype B, tracheobronchial; Sublingual gland mucin
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q9HC84
Isotype
Rabbit IgG