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MRGRD Polyclonal Antibody

CAT: 0749-ABP59323-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP59323-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MRGPRD (MAS Related GPR Family Member D) is a Protein Coding gene. Among its related pathways are ACE Inhibitor Pathway, Pharmacodynamics. GO annotations related to this gene include G-protein coupled receptor activity. An important paralog of this gene is MRGPRX4. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca (2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin-stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G (q) and G (i) .
Description
Rabbit Anti-MRGRD Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Mas-related G-protein coupled receptor member D; Beta-alanine receptor; G-protein coupled receptor TGR7
Gene ID
116512
Accession Number
Q8TDS7
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from part region of human MRGRD protein
Clonality
Polyclonal
Tag
MRGRD
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
35kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of MRGRD protein
Observed Molecular Weight
35
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Mas-related G-protein coupled receptor member D; Beta-alanine receptor; G-protein coupled receptor TGR7
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q8TDS7
Isotype
Rabbit IgG

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