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MIA3 Polyclonal Antibody

CAT: 0749-ABP59272-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP59272-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MIA3 (MIA Family Member 3, ER Export Factor) is a Protein Coding gene. Plays a role in the transport of cargos that are too large to fit into COPII-coated vesicles and require specific mechanisms to be incorporated into membrane-bound carriers and exported from the endoplasmic reticulum. This protein is required for collagen VII (COL7A1) secretion by loading COL7A1 into transport carriers. It may participate in cargo loading of COL7A1 at endoplasmic reticulum exit sites by binding to COPII coat subunits Sec23/24 and guiding SH3-bound COL7A1 into a growing carrier. Does not play a role in global protein secretion and is apparently specific to COL7A1 cargo loading. However, it may participate in secretion of other proteins in cells that do not secrete COL7A1. It is also specifically required for the secretion of lipoproteins by participating in their export from the endoplasmic reticulum.
Description
Rabbit Anti-MIA3 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Transport and Golgi organization protein 1 homolog; TANGO1; C219-reactive peptide; D320; Melanoma inhibitory activity protein 3
Gene ID
375056
Accession Number
Q5JRA6
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human MIA3 protein at amino acid sequence of 1110-1190
Clonality
Polyclonal
Tag
MIA3
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
209kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of MIA3 protein
Observed Molecular Weight
209
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Transport and Golgi organization protein 1 homolog; TANGO1; C219-reactive peptide; D320; Melanoma inhibitory activity protein 3
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q5JRA6
Isotype
Rabbit IgG

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