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LIGO1 Polyclonal Antibody

CAT: 0749-ABP59117-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP59117-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
LINGO1 (Leucine Rich Repeat And Ig Domain Containing 1) is a Protein Coding gene. Among its related pathways are p75 NTR receptor-mediated signalling and RET signaling. GO annotations related to this gene include epidermal growth factor receptor binding. An important paralog of this gene is LINGO2. Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors (PubMed: 14966521, PubMed: 15694321) . Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination (PubMed: 15895088) . Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development (By similarity) .
Description
Rabbit Anti-LIGO1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Leucine-rich repeat and immunoglobulin domain-containing protein 1; Leucine-rich repeat neuronal protein 1; Leucine-rich repeat neuronal protein 6A
Gene ID
84894
Accession Number
Q96FE5
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human LIGO1 protein at amino acid sequence of 370-450
Clonality
Polyclonal
Tag
LIGO1
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
68kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of LIGO1 protein
Observed Molecular Weight
68
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Leucine-rich repeat and immunoglobulin domain-containing protein 1; Leucine-rich repeat neuronal protein 1; Leucine-rich repeat neuronal protein 6A
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q96FE5
Isotype
Rabbit IgG

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