KLK5 Polyclonal Antibody

CAT: 0749-ABP59064-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP59064-01Size:30 µL
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Background
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. KLK5 is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. Kallikrein Related Peptidase 5 is secreted and may be involved in desquamation in the epidermis. Alternative splicing results in multiple transcript variants encoding the same protein.
Description
Rabbit Anti-KLK5 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Kallikrein-5; Kallikrein-like protein 2; KLK-L2; Stratum corneum tryptic enzyme
Gene ID
25818
Accession Number
Q9Y337
Reactivity
Human
Immunogen
Synthesized peptide derived from part region of human KLK5 protein
Clonality
Polyclonal
Tag
KLK5
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
32kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of KLK5 protein
Observed Molecular Weight
32
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Kallikrein-5; Kallikrein-like protein 2; KLK-L2; Stratum corneum tryptic enzyme
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q9Y337
Isotype
Rabbit IgG

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