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KIRR2 Polyclonal Antibody

CAT: 0749-ABP59050-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP59050-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
KIRREL2 gene encodes a type I transmembrane protein and member of the immunoglobulin superfamily of cell adhesion molecules. The encoded protein localizes to adherens junctions in pancreatic beta cells and regulates insulin secretion. Autoantibodies against the encoded protein have been detected in serum from patients with type 1 diabetes. This gene may also play a role in glomerular development and decreased expression of this gene has been observed in human glomerular diseases. This gene and the related opposite-strand gene nephrin (GeneID: 527362) are regulated by a bidirectional promoter.
Description
Rabbit Anti-KIRR2 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Kin of IRRE-like protein 2; Kin of irregular chiasm-like protein 2; Nephrin-like protein 3
Gene ID
84063
Accession Number
Q6UWL6
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human KIRR2 protein
Clonality
Polyclonal
Tag
KIRR2
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
77kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of KIRR2 protein
Observed Molecular Weight
77
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Kin of IRRE-like protein 2; Kin of irregular chiasm-like protein 2; Nephrin-like protein 3
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q6UWL6
Isotype
Rabbit IgG

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