KAT6B Polyclonal Antibody

CAT: 0749-ABP59004-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP59004-01Size:30 µL
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Background
KAT6B (Lysine Acetyltransferase 6B) is a Protein Coding gene. Diseases associated with KAT6B include Genitopatellar Syndrome and Sbbyss Syndrome. Among its related pathways are Chromatin organization. The protein encoded by KAT6B is a histone acetyltransferase and component of the MOZ/MORF protein complex. In addition to its acetyltransferase activity, the encoded protein has transcriptional activation activity in its N-terminal end and transcriptional repression activity in its C-terminal end. This protein is necessary for RUNX2-dependent transcriptional activation and could be involved in brain development. Mutations have been found in patients with genitopatellar syndrome. A translocation of KAT6B and the CREBBP gene results in acute myeloid leukemias. Three transcript variants encoding different isoforms have been found for KAT6B.
Description
Rabbit Anti-KAT6B Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Histone acetyltransferase KAT6B; Histone acetyltransferase MOZ2; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4; MYST-4; Monocytic leukemia zinc finger protein-related factor
Gene ID
23522
Accession Number
Q8WYB5
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human KAT6B protein at amino acid sequence of 1170-1250
Clonality
Polyclonal
Tag
KAT6B
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
228kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of KAT6B protein
Observed Molecular Weight
228
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Histone acetyltransferase KAT6B; Histone acetyltransferase MOZ2; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4; MYST-4; Monocytic leukemia zinc finger protein-related factor
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q8WYB5
Isotype
Rabbit IgG

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