Products for Research Use Only

IRK13 Polyclonal Antibody

CAT: 0749-ABP58966-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP58966-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
KCNJ13 (Potassium Voltage-Gated Channel Subfamily J Member 13) is a Protein Coding gene. Diseases associated with KCNJ13 include Snowflake Vitreoretinal Degeneration and Leber Congenital Amaurosis 16. Among its related pathways are Collagen chain trimerization and Dopamine-DARPP32 Feedback onto cAMP Pathway. KCNJ13 encodes a member of the inwardly rectifying potassium channel family of proteins. Members of this family form ion channel pores that allow potassium ions to pass into a cell. The encoded protein belongs to a subfamily of low signal channel conductance proteins that have a low dependence on potassium concentration. Mutations in KCNJ13 are associated with snowflake vitreoretinal degeneration. Alternate splicing results in multiple transcript variants.
Description
Rabbit Anti-IRK13 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Inward rectifier potassium channel 13; Inward rectifier K (+) channel Kir7.1; Potassium channel, inwardly rectifying subfamily J member 13
Gene ID
3769
Accession Number
O60928
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from part region of human IRK13 protein
Clonality
Polyclonal
Tag
IRK13
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
39kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of IRK13 protein
Observed Molecular Weight
39
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Inward rectifier potassium channel 13; Inward rectifier K (+) channel Kir7.1; Potassium channel, inwardly rectifying subfamily J member 13
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/O60928
Isotype
Rabbit IgG