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INSL3 Polyclonal Antibody

CAT: 0749-ABP58945-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP58945-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
INSL3 encodes a member of the insulin-like hormone superfamily. The encoded protein is mainly produced in gonadal tissues. Studies of the mouse counterpart suggest that INSL3 may be involved in the development of urogenital tract and female fertility. This protein may also act as a hormone to regulate growth and differentiation of gubernaculum, and thus mediating intra-abdominal testicular descent. Mutations in INSL3 may lead to cryptorchidism. Alternate splicing results in multiple transcript variants. INSL3 (Insulin Like 3) is a Protein Coding gene. Diseases associated with INSL3 include Cryptorchidism and Testicular Cancer. Among its related pathways are G alpha (s) signalling events and Signaling by GPCR.
Description
Rabbit Anti-INSL3 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Insulin-like 3; Leydig insulin-like peptide; Ley-I-L; Relaxin-like factor
Gene ID
3640
Accession Number
P51460
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from part region of human INSL3 protein at amino acid sequence of 10-50
Clonality
Polyclonal
Tag
INSL3
Applications
IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of INSL3
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200; ELISA 1:10000-20000; IF 1:50-200
Other Product Names
Insulin-like 3; Leydig insulin-like peptide; Ley-I-L; Relaxin-like factor
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P51460
Isotype
Rabbit IgG

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