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IL-27A Polyclonal Antibody

CAT: 0749-ABP58925-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP58925-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by IL27 is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A) . It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4 (+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4 (+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR) . IL27 (Interleukin 27) is a Protein Coding gene. Diseases associated with IL27 include Eosinophilic Granulomatosis With Polyangiitis and Visceral Leishmaniasis. Among its related pathways are IL27-mediated signaling events and Cytokine Signaling in Immune system.
Description
Rabbit Anti-IL-27A Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Interleukin-27 subunit alpha; IL-27 subunit alpha; IL-27-A; IL27-A; p28
Gene ID
246778
Accession Number
Q8NEV9
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from part region of human IL-27A protein at amino acid sequence of 1-50
Clonality
Polyclonal
Tag
IL-27A
Applications
IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of IL-27A
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200; ELISA 1:10000-20000; IF 1:50-200
Other Product Names
Interleukin-27 subunit alpha; IL-27 subunit alpha; IL-27-A; IL27-A; p28
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q8NEV9
Isotype
Rabbit IgG

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