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IL-19 Polyclonal Antibody

CAT: 0749-ABP58919-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP58919-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by IL19 is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3) . A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. IL19 (Interleukin 19) is a Protein Coding gene. Diseases associated with IL19 include Spongiotic Dermatitis and Psoriasis. Among its related pathways are Akt Signaling and PEDF Induced Signaling.
Description
Rabbit Anti-IL-19 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Interleukin-19; IL-19; Melanoma differentiation-associated protein-like protein; NG.1
Gene ID
29949
Accession Number
Q9UHD0
Reactivity
Human, Rat
Immunogen
Synthesized peptide derived from part region of human IL-19 protein at amino acid sequence of 51-100
Clonality
Polyclonal
Tag
IL-19
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
20kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of IL-19
Observed Molecular Weight
20
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:500-200; ELISA 1:10000-20000; IF 1:50-200
Other Product Names
Interleukin-19; IL-19; Melanoma differentiation-associated protein-like protein; NG.1
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q9UHD0
Isotype
Rabbit IgG

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