IGF2 Polyclonal Antibody

CAT: 0749-ABP58900-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP58900-01Size:30 µL
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Background
IGF2 encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. IGF2 (Insulin Like Growth Factor 2) is a Protein Coding gene. Diseases associated with IGF2 include Growth Restriction, Severe, With Distinctive Facies and Silver-Russell Syndrome. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and p70S6K Signaling.
Description
Rabbit Anti-IGF2 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Insulin-like growth factor II; IGF-II; Somatomedin-A; T3M-11-derived growth factor
Gene ID
3481
Accession Number
P01344
Reactivity
Human, Mouse, Rat, Pig
Immunogen
Synthesized peptide derived from part region of human IGF2 protein
Clonality
Polyclonal
Tag
IGF2
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
10kD or 19kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of IGF2 protein
Observed Molecular Weight
19
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Insulin-like growth factor II; IGF-II; Somatomedin-A; T3M-11-derived growth factor
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P01344
Isotype
Rabbit IgG

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