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IFN-β Polyclonal Antibody

CAT: 0749-ABP58894-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP58894-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
IFNB1 encodes a cytokine that belongs to the interferon family of signaling proteins, which are released as part of the innate immune response to pathogens. The protein encoded by IFNB1 belongs to the type I class of interferons, which are important for defense against viral infections. In addition, type I interferons are involved in cell differentiation and anti-tumor defenses. Following secretion in response to a pathogen, type I interferons bind a homologous receptor complex and induce transcription of genes such as those encoding inflammatory cytokines and chemokines. Overactivation of type I interferon secretion is linked to autoimmune diseases. Mice deficient for IFNB1 display several phenotypes including defects in B cell maturation and increased susceptibility to viral infection.
Description
Rabbit Anti-IFN-β Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Interferon beta; IFN-beta; Fibroblast interferon
Gene ID
3456
Accession Number
P01574
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from part region of human IFN-β protein at amino acid sequence of 91-140
Clonality
Polyclonal
Tag
IFN-β
Applications
IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of IFN-β
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200; ELISA 1:10000-20000; IF 1:50-200
Other Product Names
Interferon beta; IFN-beta; Fibroblast interferon
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P01574
Isotype
Rabbit IgG

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