Products for Research Use Only

HMGA2 Polyclonal Antibody

CAT: 0749-ABP58800-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP58800-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
HMGA2 encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that HMGA2 is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Description
Rabbit Anti-HMGA2 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
High mobility group protein HMGI-C; High mobility group AT-hook protein 2
Gene ID
8091
Accession Number
P52926
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human HMGA2 protein at amino acid sequence of 11-60
Clonality
Polyclonal
Tag
HMGA2
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
11kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of HMGA2 protein
Observed Molecular Weight
11
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
High mobility group protein HMGI-C; High mobility group AT-hook protein 2
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P52926
Isotype
Rabbit IgG