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HES5 Polyclonal Antibody

CAT: 0749-ABP58774-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP58774-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
HES5 (Hes Family BHLH Transcription Factor 5) encodes a member of a family of basic helix-loop-helix transcriptional repressors. The protein product of HES5, which is activated downstream of the Notch pathway, regulates cell differentiation in multiple tissues. Disruptions in the normal expression of HES5 have been associated with developmental diseases and cancer. HES5 is a Protein Coding gene. Diseases associated with HES5 include Valproate Embryopathy, Susceptibility To. Among its related pathways are Signaling by NOTCH1 and NOTCH2 Activation and Transmission of Signal to the Nucleus.
Description
Rabbit Anti-HES5 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Transcription factor HES-5; Class B basic helix-loop-helix protein 38; bHLHb38; Hairy and enhancer of split 5
Gene ID
388585
Accession Number
Q5TA89
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from part region of human HES5 protein at amino acid sequence of 10-90
Clonality
Polyclonal
Tag
HES5
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
18kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of HES5 protein
Observed Molecular Weight
18
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Transcription factor HES-5; Class B basic helix-loop-helix protein 38; bHLHb38; Hairy and enhancer of split 5
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q5TA89
Isotype
Rabbit IgG

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