HES5 Polyclonal Antibody

• Background :

  HES5 (Hes Family BHLH Transcription Factor 5) encodes a member of a family of basic helix-loop-helix transcriptional repressors. The protein product of HES5, which is activated downstream of the Notch pathway, regulates cell differentiation in multiple tissues. Disruptions in the normal expression of HES5 have been associated with developmental diseases and cancer. HES5 is a Protein Coding gene. Diseases associated with HES5 include Valproate Embryopathy, Susceptibility To. Among its related pathways are Signaling by NOTCH1 and NOTCH2 Activation and Transmission of Signal to the Nucleus.

• Description :

  Rabbit Anti-HES5 Polyclonal Antibody

• Product Name Alternative :

  Transcription factor HES-5; Class B basic helix-loop-helix protein 38; bHLHb38; Hairy and enhancer of split 5

• Gene ID :

  388585

• Accession Number :

  Q5TA89

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Synthesized peptide derived from part region of human HES5 protein at amino acid sequence of 10-90

• Clonality :

  Polyclonal

• Tag :

  HES5

• Applications :

  WB, ELISA

• Purification Method :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration :

  1 mg/ml

• Molecular Weight :

  18kD

• Precautions :

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions :

  Gel pack with blue ice.

• Storage Conditions :

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes :

  The antibody detects endogenous levels of HES5 protein

• Observed Molecular Weight :

  18

• Formulation :

  Liquid solution

• Buffer pH :

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

• Applications Notes :

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

• Other Product Names :

  Transcription factor HES-5; Class B basic helix-loop-helix protein 38; bHLHb38; Hairy and enhancer of split 5

• Tested Applications :

  WB, IHC, IF, IP, ELISA

• Host or Source :

  Rabbit

• Accession Number URL :

  http://www.uniprot.org/uniprot/Q5TA89

• CAS Number :

  9007-83-4

• Isotype :

  Rabbit IgG