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HCN4 Polyclonal Antibody

CAT: 0749-ABP58762-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP58762-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
HCN4 (Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 4) encodes a member of the hyperpolarization-activated cyclic nucleotide-gated potassium channels. The encoded protein shows slow kinetics of activation and inactivation, and is necessary for the cardiac pacemaking process. This channel may also mediate responses to sour stimuli. Mutations in HCN4 have been linked to sick sinus syndrome 2, also known as atrial fibrillation with bradyarrhythmia or familial sinus bradycardia. Two pseudogenes have been identified on chromosome 15.
Description
Rabbit Anti-HCN4 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
Gene ID
10021
Accession Number
Q9Y3Q4
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from part region of human HCN4 protein at amino acid sequence of 600-680
Clonality
Polyclonal
Tag
HCN4
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
132kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of HCN4 protein
Observed Molecular Weight
132
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q9Y3Q4
Isotype
Rabbit IgG

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