GRP3 Polyclonal Antibody

CAT: 0749-ABP58723-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP58723-01Size:30 µL
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Background
RASGRP3 (RAS Guanyl Releasing Protein 3) is a Protein Coding gene. Among its related pathways are RET signaling and G-protein signaling TC21 regulation pathway. GO annotations related to RASGRP3 include calcium ion binding and GTPase activator activity. The protein encoded by RASGRP3 is a guanine nucleotide exchange factor that activates the oncogenes HRAS and RAP1A. Defects in RASGRP3 have been associated with systemic lupus erythematosus and several cancers.
Description
Rabbit Anti-GRP3 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Ras guanyl-releasing protein 3; Calcium and DAG-regulated guanine nucleotide exchange factor III; Guanine nucleotide exchange factor for Rap1
Gene ID
25780
Accession Number
Q8IV61
Reactivity
Human
Immunogen
Synthesized peptide derived from part region of human GRP3 protein at amino acid sequence of 90-170
Clonality
Polyclonal
Tag
GRP3
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
75kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of GRP3 protein
Observed Molecular Weight
75
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Ras guanyl-releasing protein 3; Calcium and DAG-regulated guanine nucleotide exchange factor III; Guanine nucleotide exchange factor for Rap1
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q8IV61
Isotype
Rabbit IgG

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