Products for Research Use Only
RegisterLogin

GFRA2 Polyclonal Antibody

CAT: 0749-ABP58634-01Size: 30 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0749-ABP58634-01Size:30 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by GFRA2 is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol (GPI) -linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. GFRA2 is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for GFRA2.
Description
Rabbit Anti-GFRA2 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
GDNF receptor beta; GDNFR-beta; Neurturin receptor alpha; NRTNR-alpha; NTNR-alpha; RET ligand 2; TGF-beta-related neurotrophic factor receptor 2
Gene ID
2675
Accession Number
O00451
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human GFRA2 protein at amino acid sequence of 320-400
Clonality
Polyclonal
Tag
GFRA2
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
51kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of GFRA2 protein
Observed Molecular Weight
51
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
GDNF receptor beta; GDNFR-beta; Neurturin receptor alpha; NRTNR-alpha; NTNR-alpha; RET ligand 2; TGF-beta-related neurotrophic factor receptor 2
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/O00451
Isotype
Rabbit IgG

Related Products

CatalogName
PPT-12883Human GFRA2 Recombinant Protein
ABP58635-01GFRA3 Polyclonal Antibody
ANT-35922-100ugHuman GFRAL Antibody
ANT-35920-100ugHuman GFRA1 Antibody
ANT-12334-100ugGFRAL Monoclonal Antibody
ANT-35921-100ugHuman GFRA4 Antibody
ANT-12334-50ugGFRAL Monoclonal Antibody
ANT-13843-100ugPolyclonal Antibody
ANT-13843-50ugPolyclonal Antibody
ANT-15047-100ugWAS Polyclonal Antibody

Alternative Products

CatalogName
UB-GEN-6955GFRA2 Polyclonal Antibody
MBS9514667-01GFRA2 Rabbit Polyclonal Antibody
GTR18364380GFRA2 Rabbit Polyclonal Antibody (FITC)
WP20643-01U-Blot® GFRA2 Polyclonal Antibody
PHA12001Anti-Human GFRA2 Polyclonal Antibody
GTR18678581GFRA2 Rabbit Polyclonal Antibody (Cy3)
70R-5332GFRA2 antibody

Popular Products