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GBRR2 Polyclonal Antibody

CAT: 0749-ABP58615-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP58615-01Size:30 µL
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Background
Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA receptors, which are ligand-gated chloride channels. The protein encoded by this gene is a member of the rho subunit family and is a component of the GABA type A receptor complex. This gene exists on chromosome 6q next to the gene encoding the rho 1 subunit of the GABA type A receptor, in a region thought to be associated with susceptibility for psychiatric disorders and epilepsy. Polymorphisms in this gene may also be associated with alcohol dependence, and general cognitive ability. GABRR2 (Gamma-Aminobutyric Acid Type A Receptor Rho2 Subunit) is a Protein Coding gene. Diseases associated with GABRR2 include Alcohol Dependence and Rett Syndrome. Among its related pathways are GABAergic synapse and Ligand-gated ion channel transport.
Description
Rabbit Anti-GBRR2 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Gamma-aminobutyric acid receptor subunit rho-2; GABA (A) receptor subunit rho-2; GABA (C) receptor
Gene ID
2570
Accession Number
P28476
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from part region of human GBRR2 protein
Clonality
Polyclonal
Tag
GBRR2
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
51kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of GBRR2 protein
Observed Molecular Weight
51
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Gamma-aminobutyric acid receptor subunit rho-2; GABA (A) receptor subunit rho-2; GABA (C) receptor
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P28476
Isotype
Rabbit IgG

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